High-brightness anterograde transneuronal HSV1 H129 tracer modified using a Trojan horse-like strategy

ELT: A Trojan Horse in Disguise?

Many people believe that language teaching is a neutral practice. However, this belief is not without its own opponents. To many scholars, teaching languages cannot be devoid of teaching cultural values of the target language, which tacitly aims at denigrating cultural values of the community of the learners who are learning it. The ultimate purpose of such cultural oppression, according to the...

Trojan horse strategy in Agrobacterium transformation: abusing MAPK defense signaling.

Nuclear import of transfer DNA (T-DNA) is a central event in Agrobacterium transformation of plant cells and is thought to occur by the hijacking of certain host cell proteins. The T-DNA-associated virulence protein VirE2 mediates this process by binding to the nuclear import machinery via the host cell factor VIP1, whose role in plants has been so far unknown. Here we show that VIP1 is a trans...

Anterograde transneuronal viral tracing of central viscerosensory pathways in rats.

Previous studies demonstrated that strain H129 of herpes simplex virus-1 undergoes anterograde transneuronal transport in mice and primates after peripheral or central injection. In this study, H129 was used in rats to identify CNS regions that receive relayed viscero-sensory inputs from the stomach wall. We also examined whether transneuronal viral transport in this model is exclusively antero...

TESOL: Trojan Horse of Globalisation

E-Cigarette: a modern Trojan horse?

Smoking is an addiction that is widespread throughout the world. According to the World Health Organization (WHO), it is the leading cause of preventable death in developing countries. Despite this, therapeutic resources are limited. There are only three first-line pharmacological treatments for this severe disease: nicotine, bupropion and varenicline, all of which have low success rates, with ...